![]() 230000003899 glycosylation Effects 0.000 claims description 54.150000004676 glycans Chemical group 0.000 claims description 57.125000005647 linker group Chemical group 0.000 claims description 81.125000003147 glycosyl group Chemical group 0.000 claims description 126.238000004519 manufacturing process Methods 0.000 claims abstract description 16.229920001451 Polypropylene glycol Polymers 0.000 claims abstract description 20.229920000233 poly(alkylene oxides) Polymers 0.000 claims abstract description 106.238000004191 hydrophobic interaction chromatography Methods 0.000 claims abstract description 157.229920001223 polyethylene glycol Polymers 0.000 claims abstract description 183.238000000746 purification Methods 0.000 title abstract description 57.229920001184 polypeptide Polymers 0.000 title claims abstract description 513.Assignors: KINEALY, KYLE, DEFREES, SHAWN Publication of US20100075375A1 publication Critical patent/US20100075375A1/en Status Abandoned legal-status Critical Current Links Assigned to NOVO NORDISK A/S reassignment NOVO NORDISK A/S ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR DETAILS). Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.) Filing date Publication date Priority claimed from US84896906P external-priority Application filed by Novo Nordisk AS filed Critical Novo Nordisk AS Priority to US12/444,380 priority Critical patent/US20100075375A1/en Assigned to NOVO NORDISK A/S reassignment NOVO NORDISK A/S ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR DETAILS). Original Assignee Novo Nordisk AS Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.) Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.) Abandoned Application number US12/444,380 Inventor Shawn DeFrees Kyle Kinealy Current Assignee (The listed assignees may be inaccurate. Google Patents US20100075375A1 - Methods for the purification of polypeptide conjugates US20100075375A1 - Methods for the purification of polypeptide conjugates
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